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Table 1 Correlation between NKA concentrations and levels of pro-oxidant factors, anti-oxidant factors and cytokines after overnight incubation with LPS (100 ng/ml)

From: Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

NKA vs: Pearson r 95% CI P
Peroxidase activity 0.85 0.47 - 0.96 ***
H2O2 0.84 0.44 - 0.96 **
MDA 0.63 0.01 - 0.90 *
NO 0.83 0.41 - 0.96 **
TAC −0.49 −0.86 - 0.20 ns
GSH −0.63 −0.91 - 0.058 *
SOD −0.28 −0.77 - 0.43 ns
IL-1β 0.13 −0.55 - 0.70 ns
IL-6 0.82 0.4 0–0.96 **
IL-8 0.30 −0.40 - 0.78 ns
TNF-α 0.19 −0.50 - 0.73 ns
  1. * P<0.05, ** P<0.01, *** P<0.001, ns: not significant. GSH glutathione, IL interleukin, MDA malondialdehyde, NKA neurokinin A, NO nitric oxide, ROS reactive oxygen species, SOD superoxide dismutase, TAC total anti-oxidant capacity, TNF-α tumor necrosis factor-α