Skip to main content
Fig. 2 | Respiratory Research

Fig. 2

From: Whole Transcriptome Analysis of Pre-invasive and Invasive Early Squamous Lung Carcinoma in Archival Laser Microdissected Samples

Fig. 2

Positional enrichment and cluster analysis differentially expressed genes in PSCC and ISCC. a Genome wide positional enrichment of aberrant transcription in PSCC and ISCC. Tracks of the circos plot from outside to inside: chromosome ideogram (except Y chromosome), in which red lines demarcates the centromere; heatmap of enriched aberrant transcription in ISCC; heatmap of enriched aberrant transcription in ISCC. In both heatmaps gene up-regulation is coded in red and gene down-regulation in blue. b Cluster analysis of genes differentially expressed in low-grade PSCC, high-grade PSCC or ISCC; (i) heatmap of standardized gene expression; (ii) z-scores and (iii) histograms of standardized expression of the selected genes across normal bronchial epithelia (C), low-grade PSCC (L), high-grade PSCC (H) and ISCC (I); (iv) profiles of aberrant gene expression for the 12 identified clusters. The value in brackets represents the number of genes assigned to each of the 12 clusters

Back to article page