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Fig. 2 | Respiratory Research

Fig. 2

From: Atrial natriuretic peptide protects against bleomycin-induced pulmonary fibrosis via vascular endothelial cells in mice

Fig. 2

ANP attenuates inflammation in the lungs induced by BLM administration. Numbers of total cells (a), macrophages (b), neutrophils (c), and lymphocytes (d) in bronchoalveolar lavage (BAL) fluid on Day 7 after BLM administration. Values represent means ± SEMs (n = 5 mice per group). *p < 0.05. Lung sections from normal control mice (e), BLM-treated mice receiving vehicle (f), and BLM-treated mice receiving ANP treatment (g) obtained 7 days after BLM administration were stained with Mac-3. Representative images are shown at 200× magnification. h Mac-3–positive cells were counted in ten high-power fields (HPF). The data are expressed as means ± SE (in normal control group, n = 4; in the other groups, n = 5. *p < 0.05)

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