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Fig. 2 | Respiratory Research

Fig. 2

From: A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with moderate-to-very severe chronic obstructive pulmonary disease

Fig. 2

FEV1 AUC0–12 on Day 7 efficacy endpoint. a LSM change (95% CI) in FEV1 over 0–12 h on Day 7 by treatment; b LSM (95% CI) FEV1 AUC0–12 difference from placebo on Day 7 by treatment (mITT population). aForadil® Aerolizer® . bLSM allows for any imbalances in baseline covariates that relate to responses to be adjusted for in order to avoid bias in treatment effect estimates. AUC0–12, area under the curve from 0 to 12 h post-dose; DPI, dry powder inhaler; FEV1, forced expiratory volume in 1 s; FF, formoterol fumarate; GFF, glycopyrrolate/formoterol fumarate; GP, glycopyrrolate; LSM, least squares mean; MDI, metered dose inhaler; mITT, modified intent-to-treat

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Respiratory Research

ISSN: 1465-993X

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