Table 1 Demographic characteristics of control subjects and CF patients, with a distinction between males and females
Characteristics of control subjects and CF patients | |||
Control subjects | CF patients | p-value | |
Number of patients (n) | 22 | 20 | |
Female gender (n) | 10 (45%) | 10 (50%) | 0.77 |
Mean age (±SEM) (years) | 61.0 (±2.7) | 29.5 (±3.5) | <0.0001*** |
Characteristics of male and female CF patients | |||
Male | Female | p-value | |
Number of patients (n) (%) | 10 (50%) | 10 (50%) | 1.00 |
Mean age (±SEM) (years) | 31.6 (±3.5) | 27.3 (±6.1) | 0.052 |
Mean FEV 1 (±SEM) (% predicted) | 25.6 (±2.3) | 30.6 (±1.5) | 0.052 |
CFTR genotype (n) (%) | |||
ΔF508/ΔF508 | 4 (40%) | 6 (60%) | 0.30 |
ΔF508/other | 4 (40%) | 4 (40%) | |
other/other | 2 (20%) | 0 (0%) | |
Nasal polyposis (n) (%) | 4 (40%) | 2 (20%) | 0.33 |
High urgency listing prior to LTx (n) (%) | 1 (10%) | 4 (40%) | 0.12 |
Time on waiting list prior to LTx (±SEM) (days) | 270.6 (±147.2) | 139.6 (±61.8) | 0.25 |
CRP (±SEM) (mg/L) | 50.5 (±31.0) | 28.0 (±8.4) | 0.80 |
Differential eosinophil count on total WBC (±SEM) (%) | 2.2 (±0.9) | 2.1 (±0.8) | 0.97 |
Total IgE (±SEM) (kU/L) | 89.2 (±38.0) | 55.8 (±14.3) | 0.91 |
Colonization with P. aeruginosa (n) (%) | 8 (80%) | 6 (60%) | 0.33 |
Fungi cultured from explant lung material (n) (%) | 7 (70%) | 6 (60%) | 0.64 |
Use of inhaled corticosteroids (n) (%) | 7 (70%) | 7 (70%) | 1.00 |
Use of oral corticosteroids (n) (%) | 2 (20%) | 1 (10%) | 0.39 |
Time to last pre-LTx I.V. AB therapy (± SEM) (days) | 48.5 (±19.1) | 77.9 (±61.0) | 0.48 |