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Fig. 2 | Respiratory Research

Fig. 2

From: Bioinformatic analysis of microRNA and mRNA Regulation in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease

Fig. 2

Validation of differentially expressed miRNAs. a Expression of selected miRNAs in PBMCs of smokers and COPD patients. qRT-PCR was performed on the same RNA samples (17smokers and 14 COPD patients) as microarray analysis. Data are presented as 2(−σσCt) relative to U6. * P < 0.05, ** P < 0.01 compared with smokers by Mann Whitney U test. b Relative abundance of differentially expressed miRNAs in PBMCs of smokers and COPD patients. * P < 0.05, ** P < 0.01 compared with smokers. c Correlation analysis between miRNA expression and FEV1% predicted

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