Table 6 Comparison of groups where flow limitation is undoubted
From: Non-linear parameters of specific resistance loops to characterise obstructive airways diseases
Post methacholine Asthma (A) | Non-Openers mild COPD (B) | Openers mild COPD (C) | p value (A vs. B) | p value (A vs. C) | |
|---|---|---|---|---|---|
Subjects, n | 11 | 22 | 17 | ||
FEV1, %predicted | 75 (67–89) | 83 (76–93) | 65 (61–76) | 0.3757 | 0.0937 |
FEV1/FVC, % | 65 (60–69) | 62 (58–68) | 55 (48–61) | 0.7242 | 0.0027 |
RV/TLC, % | 32.1 (27.9–48.4) | 38.7 (35.7–40.4) | 46.6 (41.5–53.9) | <0.0001 | <0.0001 |
sGAW, 1/ kPa*sec | 0.45 (0.38–0.51) | 1.03 (0.90–1.21) | 0.61 (0.46–0.74) | <0.0001 | 0.2420 |
sG0.5 , 1/ kPa*sec | 0.63 (0.57–0.69) | 1.23 (1.06–1.38) | 1.00 (0.81–1.15) | <0.0001 | 0.0033 |
Roundness | 0.13 (0.12–0.27) | 0.09 (0.06–0.12) | 0.31 (0.22–0.41) | 0.0309 | 0.0656 |
Area of Loop | 0.14 (0.13–0.19) | 0.14 (0.10–0.20) | 0.31 (0.23–0.44) | 0.6732 | <0.0001 |
SSG, 1/sec | 2.13 (1.41–2.90) | 4.03 (2.76–4.54) | 1.67 (1.50–2.21) | 0.0022 | 0.2651 |
Point X, ml | −115 (−172–3) | −38 (−93–−19) | −92 (−29–−31) | - | - |
Asynchrony, msec | 20 (20–50) | 10 (0–43) | 40 (30–65) | 0.9999 | 0.4266 |