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Table 3 Comparison of patients with opened vs. unopened loop in mild to moderate COPD

From: Non-linear parameters of specific resistance loops to characterise obstructive airways diseases

 

Non-openers

Openers

p value

Subjects, n

22

17

 

BMI, kg/m2

24.9 (22.0–29.4)

26.8 (24.1–27.8)

0.6093

FEV1, %predicted

83 (76–93)

65 (61–76)

0.0018

DLCO, %predicted

67 (55–79)

69 (53–75)

0.6774

RV, %predicted

115 (106–133)

134 (120–150)

0.0368

TLC, %predicted

109 (99–115)

107 (102–110)

0.6793

FRC, %predicted

122 (101–135)

131 (120–142)

0.1578

RV/TLC, %

38.7 (35.7–40.4)

46.6 (41.5–53.9)

0.0007

sGAW, 1/ kPa*sec

1.03 (0.90–1.21)

0.61 (0.46–0.74)

<0.0001

sG0.5 , 1/ kPa*sec

1.23 (1.06–1.38)

1.00 (0.81–1.15)

0.0047

Roundness

0.09 (0.06–0.12)

0.31 (0.22–0.41)

<0.0001

Area of Loop

0.14 (0.10–0.20)

0.31 (0.23–0.44)

<0.0001

Asynchrony, msec

10 (0–40)

40 (30–70)

0.0097

Point X, ml

−38 (−93–−19)

−92 (−209–−31)

0.0827

Point Y, ml/sec

−251 (−379–−177)

−251 (−406–−139)

0.7107

b 0

4.10 (2.92–5.56)

1.63 (1.18–2.58)

0.0013

b 1

−3.47 (−8.11–1.16)

−2.40 (−3.95–0.20)

0.3080

b 2

1.42 (−2.87–3.27)

0.77 (−0.46–1.97)

0.5132

SSG, 1/sec

4.03 (2.76–4.54)

1.67 (1.50–2.21)

<0.0001

Pole1

0.84 (0.67–0.96)

0.93 (0.82–0.97)

0.2301

Pole2

0.64 (0.26–0.89)

0.86 (0.49–0.95)

0.1216

  1. Values are median and IQR; Differences between groups controlled with T-test or Mann–Whitney test depending of distribution