The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)

Table 1 Demographic and lung function data for participants

Study groups	NC		NLFS	CAL
	LA biopsy	SA resected tissue
n	9	9	8	29
Male/female	4/5	6/3	3/5	13/16
Age (years)	65 (52–72)	52 (42–63)	72 (52–79)	66 (42–85)
Smoking history (pack years)	N/A	N/A	23 (0.3–60)	32.5 (0–72)
FEV₁/FVC (%)^a	N/A	N/A	79.5 (70–90)	68 (54.9–78)
FEF_25–75% (L/sec)^a	N/A	N/A	81.5 (70–116)	41.5 (20–69)

Data expressed as median and range
CAL chronic airflow limitation, FEV ₁ forced expiratory volume in 1 s, FVC forced vital capacity, FEF _25–75% forced expiratory flow at 25–75%, LA large airway, NC normal control, NLFS normal lung function smoker, N/A not any, SA small airway
^aPost bronchodilator values after 400 μg of salbutamol

ISSN: 1465-993X