Table 3 Comparison of e-Cigarette and conventional cigarette users (dual users) vs e-Cigarette only users (single users) at 12- and 24-month follow-up visits

COPD EC users reducing cig use (dual users)

(n = 11)

(n = 11)

(n = 11)

 Sex

10 M, 1 F

10 M, 1 F

11 M

 % Smoking reduction compared to baseline

-

82.6 (±4.8)

85.1 (±4.7)

 post-BD FEV1^a (L)

1.23 (0.94, 1.6)

1.20 (0.91, 1.70)

1.28 (0.92, 1.96)

 post-BD FVC^a (L)

2.34 (2.04, 2.86)

2.35 (2.07, 2.89)

2.57 (2.22, 2.93)

 %FEV/FVC^a

50.9 (47, 61.2)

51.2 (46.9, 64)

51.8 (43.3, 65.7)

 Cig/day^b

23.7 (±5.4)

4 (±1.2)

3.5 (±1.3)

 CAT score^a

25 (19.5, 26.5)

20 (18, 22)

18 (15, 22)

 COPD Exacerbations^b

2.6 (±0.8)

2.3 (±0.8)

1.5 (±0.8)

COPD EC users ceasing cig use (single users)

(n = 13)

(n = 13)

(n = 13)

 Sex

10 M, 3 F

10 M, 3 F

9 M, 3 F

 Smoking reduction compared to baseline

-

-

-

 post-BD FEV1^a (L)

1.32 (0.96, 1.76)

1.26 (0.94, 1.72)

1.3 (0.95, 1.63)

 post-BD FVC^a (L)

2.57 (2.01, 2.65)

2.57 (1.92, 2.72)

2.44 (1.72, 2.82)

 %FEV/FVC^a

61.9 (50.8, 66.4)

61.5 (50.6, 65.6)

61.5 (50, 65.2)

 Cig/day^b

20.2 (±2.7)

-

-

 CAT score^a

20 (17, 24)

16 (14, 18)

17 (15, 20)

 COPD Exacerbations^b

2.07 (±1.0)

1.3 (±1)

1.4 (±1)