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Fig. 7 | Respiratory Research

Fig. 7

From: Pulmonary hypertension and vascular remodeling in mice exposed to crystalline silica

Fig. 7

Expression of vascular-specific genes. Analysis of gene expression in the lung of silica- and bleomycin-treated mice (panels a-d). Expression of genes was analyzed 28 days following silica instillation and 21 days following bleomycin instillation. Whole lung mRNA levels for PECAM-1 (CD31), platelet factor 4 (PF4), nestin and endothelin 1 were determined using real-time PCR and normalized to beta-acting expression (β-Actin). The results are shown as mean ± SEM, *p < 0.05 when compared to control lung, One Way ANOVA with Holm-Sidak post test

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