Fig. 6
From: Pulmonary hypertension and vascular remodeling in mice exposed to crystalline silica
Muscularization of pulmonary arteries in silica- and bleomycin-treated mice. Lung sections were stained with vWF (red) and alpha-smooth muscle actin (green) specific antibodies. Nuclei were stained using DAPI (blue). Representative images of non-muscularized (a), partially muscularized (b) and fully-muscularized (c) arteries showed on left side. Quantitative analysis of pulmonary arteries remodeling presented on right side. Significant increase in partially-muscularized and fully muscularized arteries was detected in silica (0.4Â g/kg) and bleomycin-treated lungs