Fig. 3
From: The impact of low-frequency, low-force cyclic stretching of human bronchi on airway responsiveness
Effect of low-frequency, low-force cyclic stretching on the early mRNA-expression of genes involved in the WNT signaling pathway (WNT2, WNT3A, WNT4, WNT5A, WNT7B and FZD7), the MAPK signaling pathway (MAPK1 and MAPK9), extracellular matrix modulation (ELN and LAMC1) or actin filament modulation (COL4A1), stress or inflammation (IL8/CXCL8, MAP3K14, and MAPK14) or apoptosis (MYC) or the genes coding for type-L calcium channels (CACNA1S), cholinergic receptors (CHRNA7) or the β2−adrenergic receptor (ADRB2) in 9 human bronchial rings. Values were determined with RT-qPCR and are quoted as the relative expression level (2-ΔCt), where ∆Ct is the difference between the target gene’s Ct and the mean Ct for simultaneously amplified reference genes. * P < 0.05 for stretched bronchi versus paired, non-stretched control bronchi