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Table 1 Descriptive statistics on weighted vs. un-weighted confounders

From: Evaluation of the use of Swedish integrated electronic health records and register health care data as support clinical trials in severe asthma: the PACEHR study

Variable

EHR (unweighted)

EHR (weighted)

RCT total population

n

Mean (SD %)

n

Mean (SD %)

N

Mean (SD %)

Age

240

50.3 (14.8)

239

50.6 (23.7)

451

50.1 (12.3)

BMI (kg/m2)

239

28.0 (5.8)

239

27.0 (7.6)

451

27.3 (4.9)

FEV (% predicted)

240

84.1 (19.0)

239

63.1 (31.8)

450

68.7 (18.0)

GINA 5 n (%)

240

101.0 (42.1%)

239

70.0 (13.3%)

451

77.0 (17.1%)

Male n (%)

240

76.0 (31.7%)

239

106.1 (40.1%)

451

155.0 (34.4%)

Neutrophils (unit)

77

6.2(2.8)

77

6.0 (2.8)

426

4.7 (2.0)

One year Pre-index Exacerbations rate

240

3.0 (1.6)

239

2.5 (1.5)

451

2.6 (0.9)

  1. Weighted and unweighted patient characteristics of the EHR population compared to the combined placebo and treatment groups in RCT