Table 4 COPD-related Genes from WGCNA blue comethylation module
CpG site | Nearest Gene | Gene Significance to COPD | Gene Significance p-value | Module Membership to Blue Module | Module Membership p-value |
|---|---|---|---|---|---|
cg22566906 | GRASP | -0.52 | 7.06E-27 | 0.76 | 8.62E-71 |
cg27461196 | FXYD1/LGI4 | -0.52 | 1.19E-26 | 0.76 | 7.10E-70 |
cg16361890 | MAML1 | -0.52 | 1.98E-26 | 0.83 | 1.28E-93 |
cg14700707 | NOTCH4 | -0.52 | 2.61E-26 | 0.72 | 1.52E-59 |
cg25634666 | FOLR3 | -0.51 | 1.82E-25 | 0.78 | 3.50E-76 |
cg12971694 | CD72 | -0.51 | 2.11E-25 | 0.84 | 7.77E-99 |
cg24489015 | LPO | -0.50 | 7.21E-25 | 0.79 | 2.57E-78 |
cg00333528 | GABRR1 | -0.50 | 7.29E-25 | 0.83 | 5.25E-94 |
cg02635407 | SH3TC1 | -0.50 | 7.93E-25 | 0.85 | 1.02E-102 |
cg00615377 | RBFOX2 | -0.49 | 1.25E-23 | 0.87 | 1.20E-111 |
cg11394785 | MAML1 | -0.48 | 5.73E-23 | 0.78 | 2.39E-75 |
cg17356733 | IFNGR2 | -0.48 | 1.79E-22 | 0.83 | 6.93E-95 |
cg18390025 | ELOVL3 | -0.48 | 1.83E-22 | 0.84 | 4.19E-97 |
cg02181506 | SERPINA1 | -0.45 | 8.76E-20 | 0.74 | 7.93E-65 |
cg04536922 | FAM13A | -0.45 | 1.62E-19 | 0.87 | 1.49E-114 |
cg00431050 | ELOVL3 | -0.39 | 1.57E-14 | 0.69 | 3.83E-52 |
cg18328334 | TNS1 | -0.37 | 2.87E-13 | 0.54 | 4.75E-29 |
cg04845063 | FAM13A | -0.36 | 1.38E-12 | 0.80 | 1.97E-84 |
cg12585943 | PPT2 | -0.29 | 2.72E-08 | 0.59 | 5.39E-35 |
cg22563815 | CHRNA5 | -0.29 | 2.84E-08 | 0.52 | 1.72E-26 |
cg16505550 | PPAP2B | -0.23 | 7.46E-06 | 0.38 | 5.96E-14 |
cg04603031 | CHRNA3 | -0.22 | 2.28E-05 | 0.66 | 7.85E-47 |
cg27486427 | RARB | -0.22 | 3.08E-05 | 0.90 | 2.67E-130 |
cg00318573 | CHRNA4 | -0.19 | 1.77E-04 | 0.58 | 9.87E-35 |
cg03874127 | ARMC2 | -0.18 | 6.61E-04 | 0.57 | 2.36E-33 |
cg25229172 | CCDC38 | -0.17 | 8.09E-04 | 0.43 | 8.49E-18 |
cg19848683 | MECOM | -0.14 | 6.09E-03 | 0.75 | 5.35E-67 |
cg13701109 | ADAMTS19 | -0.14 | 7.38E-03 | 0.71 | 1.57E-57 |
cg06334284 | PPAP2B | -0.13 | 1.11E-02 | 0.82 | 7.50E-92 |
cg14228238 | MECOM | -0.12 | 2.55E-02 | 0.60 | 1.41E-37 |
cg14580567 | HHIP | -0.04 | 4.24E-01 | 0.61 | 3.32E-39 |
cg21750589 | ZKSCAN3/ZSCAN31 | -0.04 | 4.95E-01 | 0.26 | 4.78E-07 |