Table 3 Characteristics of Patients who measured Sirt1 protein expression

GOLD

-

Stage I

Stage II

Stage III, IV

Number of patients

12

5

20

11

Age (years)

69.6 ± 6.4

74.2 ± 5.5

75.9 ± 7.7

74.2 ± 7.6

Gender (Male/Female)

(12/0)

(4/1)

(19/1)

(10/1)

FVC predict (%)

99.2 ± 15.6

114.1 ± 5.4

97.2 ± 11.6

81.9 ± 17.5*

FEV1/FVC (%)

77.1 ± 7.6

59.4 ± 7.6*

51.0 ± 9.4*

32.7 ± 6.7*

FEV1% predict

96.6 ± 14.3

88.2 ± 8.0

63.5 ± 7.3*

34.2 ± 9.2*

Smoking (Pack years)

48.1 ± 31.7

43.0 ± 11.8

56.3 ± 31.7

68.3 ± 32.9

Current smoker (no.)

3

0

6

0

 LABA

-

4

17

10

 LAMA

-

3

16

8

 ICS

-

2

6

7