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Fig. 4 | Respiratory Research

Fig. 4

From: Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease

Fig. 4

Gene expression in blood samples from patients with moderate and severe COPD between current smokers and former smokers. a The graphs show mean and individual data from the RT-PCR analysis of CD31, CD34, IL-6, Sirt1 mRNA, miR-34a, and miR-126-3p expressions in blood cells between current smokers and former smokers (Ex-smokers) in subjects with severe COPD. We observed a tendency toward decreased IL-6 expression in ex-smokers compared to that in current smokers. b The graphs show mean and individual data from RT-PCR analysis of IL-6 mRNA expression in blood cells between current smokers and ex-smokers in subjects with moderate and severe COPD. c A strong positive correlation was seen between IL-6 and Sirt1 mRNA expression among current smokers with severe COPD. A weak positive correlation was seen between IL-6 and Sirt1 mRNA expression among ex-smokers with severe COPD. Data are expressed as mean ± SD

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