AUC (95 % CI) | P value | |
---|---|---|
Serological biomarkers | ||
C6M | 0.724 (0.695–0.752) | - |
Pro-C6 | 0.722 (0.692–0.751) | - |
CRP | 0.719 (0.689–0.747) | - |
C6M + Pro-C6 | 0.796 (0.769–0.822) | - |
C6M + CRP | 0.727 (0.697–0.755) | - |
Pro-C6 + CRP | 0.775 (0.746–0.802) | - |
C6M + Pro-C6 + CRP | 0.791 (0.762–0.818) | - |
Clinical models | ||
Age + BODE + Previous exacerbations | 0.750 (0.721–0.778) | |
+ C3M | 0.803 (0.776–0.829) | 0.084 |
+ CRPM | 0.807 (0.780–0.832) | 0.044 |
+ C6M | 0.813 (0.786–0.837) | 0.038 |
+ Pro-C6 | 0.826 (0.799–0.851) | 0.071 |
+ CRP | 0.811 (0.783–0.836) | 0.046 |
+ C6M + Pro-C6 | 0.867 (0.843–0.889) | 0.001 |
+ C6M + CRP | 0.817 (0.790–0.842) | 0.023 |
+ C6M + CRPM | 0.818 (0.791–0.842) | 0.036 |
+ Pro-C6 + CRP | 0.863 (0.837–0.886) | 0.001 |
+ Pro-C6 + CRPM | 0.864 (0.840–0.886) | 0.003 |
+ C6M + Pro-C6 + CRP | 0.871 (0.846–0.893) | 0.0004 |
+ C6M + Pro-C6 + CRPM | 0.871 (0.847–0.893) | 0.001 |