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Table 1 Clinical characteristics of patients

From: Extracellular ATP is involved in dsRNA-induced MUC5AC production via P2Y2R in human airway epithelium

  Healthy subjects (n = 5) COPD (n = 5)
Sex (Male/Female) 1/4 5/0
Age (years) 69.5 ± 6.06 70.6 ± 3.84
Ex-smoker 1 5
smoking history (pack-year) 8.0 ± 17.9 76.7 ± 73.7*
FVC (L) 2.82 ± 0.24 3.30 ± 0.38*
FVC % predicted 115 ± 12.3 96.0 ± 7.89*
FEV1 (L) 2.18 ± 0.15 2.14 ± 0.50
FEV1 % predicted 113 ± 19.2 74.3 ± 17.0*
FEV1/FVC (%) 77.5 ± 9.54 64.0 ± 10.2
DLCO/VA % predicted 102 ± 10.5 86.2 ± 8.62*
  1. COPD chronic obstructive pulmonary disease; pack-year: 1 year smoking 20 cigarettes-day; FVC forced vital capacity; FEV1 forced expiratory volume in one second; DLCO diffusing capacity of the lung for carbon monoxide; VA alveolar volume. Values are mean ± SE. *p < 0.05 compared to healthy subjects