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Table 6 Association of allergy in children with % CD4+CD25+ FOXP3+ T in neonate CBMCs

From: Maternal allergic disease history affects childhood allergy development through impairment of neonatal regulatory T-cells

 

Adjusted OR (95 % CI) P-value

Unstimulated

LPA-stimulated

PPG-stimulated

All allergies

0.51 (0.18–1.51) 0.228

0.65 (0.23–1.85) 0.416

0.12 (0.04–0.43) 0.01

Allergic wheezing

0.017 (0.001–0.46) 0.016

2.15 (0.35–13.39) 0.41

0.36 (0.046–2.77) 0.32

Allergic rhinitis

0.49 (0.148–1.60) 0.23

0.39 (0.12–1.28) 0.12

0.26 (0.074–0.91) 0.035

Allergic eczema

1.08 (0.36–3.29) 0.88

0.57 (0.18–1.80) 0.34

0.16 (0.044–0.56) 0.04

  1. Data in boldface are significant with P ≤ 0.05. Data were adjusted for maternal allergy, environmental and social factors