Fig. 2From: Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanism a The effect of CSE on IL-13 transcription. The effect of knockdown of IL-13 transcripts on OPN (b) and ADA mRNA expression (c), OPN (d) and ADA (e). The effect of knockdown of STAT6 on OPN (f) and ADA mRNA expression (g). Results are expressed as the means (±SD) values of six independent experiments from 6 COPD patients. **, p < 0.001 vs controlBack to article page