Table 1 Characteristics of IPAH patients and Control group
Parameter (units) | IPAH patients, n=10 | Controls, n=8 | p |
|---|---|---|---|
age (years) | 41 (37-50) | 54 (37-60) | 0.24 |
sex (M) | 3 (30 %) | 3 (38 %) | 0.87 |
NT-proBNP (pg/ml) | 1204 (837-2327) | 63 (28.5-135,4) | 0.0002 |
ET-1 (ng/ml) | 2.54 (2.06-2.79) | 0.63 (0.49-0.86) | 0.0002 |
6MWD (m) | 397.5 (345-420) | 460 (420-630) | 0.02 |
Hb (g/dl) | 15.4 (14.4-16.0) | 13.3 (11.8-14.4) | 0.01 |
PAP mean (mmHg) | 52 (43-56) | 12 (10-14.5) | 0.0004 |
PWP (mmHg) | 6 (3-8) | 7.5 (6-9.5) | 0.35 |
RAP mean (mmHg) | 5 (4-7) | 2 (2-3) | 0.002 |
CI (l/min/m2) | 1.9 (1.4-2.3) | 3.2 (2.5-3.5) | 0.002 |
PAR (dyn*s*cm-5) | 1111 (888-1260) | 77.9 (32.1-97.6) | 0.0004 |