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Fig. 2 | Respiratory Research

Fig. 2

From: Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats

Fig. 2

a-f IHC staining of CF6 in the sham group (a, d), MCT-vehicle group (b, c) and MCT plus left pneumonectomy group (e, f) at 4 w after MCT injection. Quantification of serum CF6 levels at 1 w, 2 w, 3 w, 4 w by ELISA in MCT-vehicle group (g) and MCT plus left pneumonectomy model (i). Relative CF6 mRNA levels in MCT-vehicle group (h) and MCT plus left pneumonectomy model (j), as detected by quantitative RT-PCR. The results are expressed as the mean ± SD. Bar = 30 μm. **p < 0.01 and *p < 0.05. IHC, immunohistochemistry; MCT, monocrotaline; PAH, pulmonary artery hypertension; P, pneumonectomy

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