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Table 1 Characterisation of spark generated silver nanoparticles and lung burden on each of the exposure conditions for the two rat strains

From: Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague–Dawley rats

 

Sprague–Dawley rats

Brown-Norway rats

Control

Low dose

High dose

Control

Low dose

High dose

Count Median Diameter (nm)

-

13.4 ± 1.0

14.1 ± 2.3

-

15.9 ± 0.8

15.7 ± 2.8

Geometric Standard Deviation

-

1.60 ± 0.03

1.58 ± 0.06

-

1.58 ± 0.02

1.56 ± 0.06

Concentration /cm3

<1

(4.50 ± 0.21) x 107

(4.55 ± 0.70) x 107

<1

(3.89 ± 0.18) x 107

(3.68 ± 0.48) x 107

Mass concentration (μg/m3)

-

801 ± 33

670 ± 49

-

791 ± 32

617 ± 25

Exposure duration (mins)

720

180

720

720

180

720

Lung burden (μg)

0

8

28

0

8

26

Alveolar dose (μg)

0

6

19

0

6

18