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Fig. 3 | Respiratory Research

Fig. 3

From: Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs

Fig. 3

Quantification of total basal cells and KRT5+ and KRT14+ basal cell subpopulations in the healthy human lung. Cells were counted according to their positivity for p63, KRT5 or KRT14 immunostaining in conducting airways (1 donor, 2 samples, n = 7 assessed fields/sample) and in distal airways (5 donors, 1-3 samples/donor, n = 34 assessed bronchioles). Data are expressed as mean ± SEM. A 2-Way ANOVA with Bonferroni post-test revealed a significant interaction according to the type of airway (Conducting versus distal, p < 0.0001); all 6 quantified populations were significantly different between conducting and distal airways (***p < 0.001). Each dataset (conducting and distal) was then compared separately with a One-Way ANOVA test: ***p < 0.001 versus “Conducting KRT5+”, ### p < 0.001 versus “Distal KRT5+

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