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Table 7 Spearman’s correlation analysis between MMPs/TIMP4 ratios and emphysema sub-types

From: Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

  MMP-3/TIMP-4 MMP-7/TIMP-4 MMP-8/TIMP-4 MMP-9/TIMP-4 MMP-10/TIMP-4 MMP-12/TIMP-4
Mild CLE 0.03 −0.02 −0.06 0.03 0.16 0.01
Moderate CLE 0.35 0.25 0.43* 0.15 0.30 −0.12
Severe CLE 0.41* 0.20 0.32 0.07 0.22 −0.21
Panlobular 0.54** 0.24 0.29 0.11 0.36* 0.01
Paraseptal 0.42* 0.32 0.38* 0.16 0.32 −0.14
Normal −0.35 −0.20 −0.32 −0.09 −0.34 0.21
  1. Spearman’s rho values given
  2. N = 31. *p < 0.05; **p < 0.01