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Table 1 Characteristics of participants included in the study

From: Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

  COPD (n = 24) Preserved lung function (n = 8) P value
Age 66.0 (12.0) 56.0 (18.0) 0.064
Male 16 6 >0.999
Current smoker 11 5 0.685
Pack Years 39 (39.8) 32.25 (23.8) 0.268
FEV1 % predicted 69.00 (21.0) 108.00 (20.3) <0.001*
FEV1/FVC 54.50 (10.8) 78.00 (9.5) <0.001*
Mild CLE 33.8 (8.3) 31.9 (9.5) 0.44
Moderate CLE 21.3 (15.3) 7.1 (9.2) 0.008*
Severe CLE 0.9 (2.0) 0.0 (0.0) 0.008*
Panlobular 2.7 (1.1) 0.0 (0.0) 0.048*
Paraseptal 6.9 (3.9) 3.7 (3.0) 0.014*
Non-emphysema 34.6 (20.6) 53.5 (21.4) 0.011*
  1. Values are given as medians (IQR). Tissue sub-types given as median % of CT lung volume classified as particular sub-type
  2. Male and current smokers given as number of subjects
  3. Tissue sub-types given for 31 subjects
  4. *p < 0.05. Fisher’s exact test for male and current smoker. Mann-Whitney U-test for all other variables