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Table 1 Characteristics of participants included in the study

From: Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

 

COPD (n = 24)

Preserved lung function (n = 8)

P value

Age

66.0 (12.0)

56.0 (18.0)

0.064

Male

16

6

>0.999

Current smoker

11

5

0.685

Pack Years

39 (39.8)

32.25 (23.8)

0.268

FEV1 % predicted

69.00 (21.0)

108.00 (20.3)

<0.001*

FEV1/FVC

54.50 (10.8)

78.00 (9.5)

<0.001*

Mild CLE

33.8 (8.3)

31.9 (9.5)

0.44

Moderate CLE

21.3 (15.3)

7.1 (9.2)

0.008*

Severe CLE

0.9 (2.0)

0.0 (0.0)

0.008*

Panlobular

2.7 (1.1)

0.0 (0.0)

0.048*

Paraseptal

6.9 (3.9)

3.7 (3.0)

0.014*

Non-emphysema

34.6 (20.6)

53.5 (21.4)

0.011*

  1. Values are given as medians (IQR). Tissue sub-types given as median % of CT lung volume classified as particular sub-type
  2. Male and current smokers given as number of subjects
  3. Tissue sub-types given for 31 subjects
  4. *p < 0.05. Fisher’s exact test for male and current smoker. Mann-Whitney U-test for all other variables
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Respiratory Research

ISSN: 1465-993X

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