From: Risk factors for an acute exacerbation of idiopathic pulmonary fibrosis
 | HR | (95 % CI) | P Value |
---|---|---|---|
Treatment after diagnosis | |||
Immunosuppressive agent | |||
 Unadjusted | 2.40 | (0.96 to 6.02) | 0.062 |
Cardiovascular diseases | |||
 Unadjusted | 2.08 | (0.91 to 4.54) | 0.086 |
 Adjusteda | 2.37 | (1.03 to 5.44) | 0.042 |
GAP stage (≥II) | |||
 Unadjusted | 4.02 | (1.68 to 9.64) | 0.002 |
 Adjusteda | 3.63 | (1.47 to 8.93) | 0.005 |
Serum markers | |||
LDH, U/L, Cut off point = 180 | |||
 Unadjusted | 2.49 | (0.74 to 8.37) | 0.139 |
 Adjusteda | 2.24 | (0.66 to 7.63) | 0.198 |
KL-6, U/mL, Cut off point = 946 | |||
 Unadjusted | 1.46 | (0.67 to 3.18) | 0.340 |
 Adjusteda | 1.45 | (0.67 to 3.17) | 0.345 |
SP-D, ng/mL, Cut off point = 194.7 | |||
 Unadjusted | 3.49 | (1.36 to 8.94) | 0.009 |
 Adjusteda | 3.21 | (1.21 to 8.48) | 0.019 |
BAL fluid findings | |||
Lymphocytes, %, Cut off point = 10.15 | |||
 Unadjusted | 1.96 | (0.93 to 4.14) | 0.077 |
 Adjusteda | 1.99 | (0.94 to 4.21) | 0.072 |
Neutrophils, %, Cut off point = 1.77 | |||
 Unadjusted | 2.48 | (0.73 to 8.45) | 0.147 |
 Adjusteda | 2.21 | (0.63 to 7.69) | 0.213 |
Eosinophils, %, Cut off point = 3.21 | |||
 Unadjusted | 2.42 | (1.03 to 5.68) | 0.043 |
 Adjusteda | 2.20 | (0.92 to 5.25) | 0.075 |