From: Risk factors for an acute exacerbation of idiopathic pulmonary fibrosis
 | Non-AE (N = 41) | AE (N = 24) | log-rank P Value |
---|---|---|---|
Smoking | |||
 S or Ex | 32 | 20 | 0.918 |
 N | 9 | 4 |  |
Cardiovascular diseases | |||
 Yes | 10 | 8 | 0.042 |
 No | 31 | 16 |  |
GAP stage | |||
 II or III | 11 | 12 | 0.002 |
 I | 25 | 10 |  |
Serum markers | |||
LDH | |||
  ≥ 180 | 32 | 22 | 0.048 |
  < 180 | 9 | 2 |  |
KL-6 | Â | Â | Â |
  ≥ 946 | 18 | 16 | 0.292 |
  < 946 | 21 | 8 |  |
SP-D | |||
  ≥ 194.7 | 22 | 18 | 0.014 |
  < 194.7 | 17 | 6 |  |
BAL fluid findings | |||
Lymphocytes | |||
  ≥ 10.15 | 13 | 13 | 0.085 |
  < 10.15 | 28 | 11 |  |
Neutrophils | |||
  ≥ 1.77 | 34 | 22 | 0.048 |
  < 1.77 | 7 | 2 |  |
Eosinophils | |||
  ≥ 3.21 | 21 | 17 | 0.009 |
  < 3.21 | 20 | 7 |  |
Treatment after the diagnosis | |||
Steroid | |||
 Yes | 7 | 8 | 0.443 |
 No | 34 | 16 |  |
Immunosuppressive agent | |||
 Yes | 3 | 6 | 0.009 |
 No | 38 | 18 |  |
Pirfenidone | |||
 Yes | 8 | 6 | 0.963 |
 No | 33 | 18 |  |
NAC | |||
 Yes | 8 | 5 | 0.547 |
 No | 33 | 19 |  |