Risk factors for mortality in patients admitted to intensive care units with pneumonia

Respiratory Research

Table 4 Sensitivity analysis results from multivariable analyses evaluating the relationship between independent variables and 30-day hospital and ICU mortality

Independent variables	Hospital mortality^a		ICU mortality^b
Independent variables	HR (95 % CI)	P-value	HR (95 % CI)	P-value
Baseline variables
Male	1.39 (0.96-1.96)	0.090	1.30 (0.85-2.04)	0.22
APACHE II score^c	1.29 (1.14-1.47)	<0.001	1.20 (1.06-1.37)	0.004
History of malignancy	1.46 (0.70-3.03)	0.31	-^d	-^d
End-stage renal disease	1.13 (0.38-3.39)	0.82	-^d	-^d
Chronic respiratory disease	1.49 (0.98-2.27)	0.063	1.45 (0.92-2.28)	0.11
Chronic heart failure	2.25 (1.16-4.34)	0.017	2.57 (1.32-5.02)	0.006
History of venous thromboembolism	0.76 (0.28-2.09)	0.59	0.52 (0.13-2.12)	0.36
Immunocompromise	1.48 (0.91-2.41)	0.12	1.43 (0.85-2.39)	0.17
Daily intervention variables
Inotropes/vasopressors	1.21 (0.84-1.75)	0.31	1.07 (0.71-1.62)	0.75
Dialysis	2.29 (1.03-5.11)	0.042	1.33 (0.59-2.98)	0.49
Red blood cell transfusion	1.20 (0.62-2.30)	0.59	1.38 (0.67-2.84)	0.39
Central venous catheterization	1.50 (0.86-2.63)	0.15	1.12 (0.62-2.01)	0.72
Acetylsalicylic acid or clopidogrel	1.36 (0.93-2.00)	0.11	-^d	-^d
Erythropoietin-stimulating agents	-^e	-^e	1.39 c0.32-6.04)	0.66

HR hazard ratio, CI confidence interval, BMI body mass index, APACHE Acute Physiology and Chronic Health Evaluation
^aThere were 122 deaths for 30-day hospital mortality; No multicollinearity detected
^bThere were 97 deaths for 30-day hospital mortality; No multicollinearity detected
^cResults for 5-point increase
^dNot included in the multivariable analysis for ICU mortality
^eNot included in the multivariable analysis for hospital mortality

ISSN: 1465-993X