Table 2 Deposited fractions in extrathoracic (ET) and thoracic (TH) regions for the different types of polydisperse radioactive aerosols. Results are expressed in ratio (%) of the total deposited fraction (mean ± SD). Comparison of experimental results obtained with the chimeric model to baboon and human in vivo experimentations realized in previous studies [11, 17]
From: Micron-sized and submicron-sized aerosol deposition in a new ex vivo preclinical model
[0.15 μm–0.5 μm] | [0.25 μm–1 μm] | [1 μm–9 μm] | ||
|---|---|---|---|---|
Chimeric model (Supine position) | ET | 11 ± 4 % | 22 ± 5 % | 65 ± 11 % |
TH | 89 ± 4 % | 78 ± 5 % | 35 ± 11 % | |
Human (Erect position) | ET | NC | NC | 72 ± 14 % |
TH | NC | NC | 28 ± 12 % | |
Baboon (Erect position) | ET | 16 ± 4 % | 49 ± 8 % | 72 ± 17 % |
TH | 84 ± 4 % | 51 ± 8 % | 28 ± 17 % |