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Fig. 3 | Respiratory Research

Fig. 3

From: Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor

Fig. 3

AlamarBlue was investigated as a measure of metabolic activity in fibrotic and control lung slices. a) Left graph depicts the metabolic activity in lung slices coming from control and BLM animals euthanized after 7 days, before and after 48 h of cultivation. Right graph depicts the metabolic activity in lung slices coming from control and BLM animals euthanized after 14 days, before and after 48 h of cultivation. b) The metabolic activity in lung slices coming from control and BLM animals euthanized after 14 days, before and after 48 h of cultivation. w/o: Williams E medium without any intervention; IBMX: Williams E medium + 100 μM IBMX; GM6001: Williams E medium + 10 μM GM6001

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Respiratory Research

ISSN: 1465-993X

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