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Fig. 1 | Respiratory Research

Fig. 1

From: Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor

Fig. 1

Levels of N-terminal propeptide of collagen type I (a), MMP-2, 9 and 13 generated fragments of collagen type I (b), N-terminal propeptide of collagen type III (c), MMP-9 generated fragments of collagen type III (d) and MMP-7 generated fragments of elastin (e) in the supernatants of the PCLS model after 48 h of culturing from animals euthanized seven days after last BLM or vehicle dosing and animals euthanized 14 days after the last dosing. w/o: Williams E medium without intervention. Significance level: *p < 0.05, **p < 0.01, *** p < 0.001, ****p < 0.0001

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Respiratory Research

ISSN: 1465-993X

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