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Fig. 5 | Respiratory Research

Fig. 5

From: Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses

Fig. 5

Inflammation score in H&E-stained lung tissues from (a) IAV-infected or (b) RSV-infected or (c) Poly (I:C) instilled mice with or without exposure to CS on day 14 post infection. The arrows in FA-IAV image indicate neutrophilic and monocytic infiltrates at the bronchovascular junction, in the CS-Vehicle image indicate alveolar macrophage accumulation, in CS-IAV indicate infiltrates of monocytes, lymphocytes and neutrophils. The arrows in FA-RSV indicate infiltrates of lymphocytes and some macrophages, in CS-RSV images indicate infiltrates of lymphocytes and monocytes around the vessels, and neutropils and necrotic cell debris in the airways. The arrows in FA-poly(I;C) and CS-Poly(I:C) images indicate infiltrates of macrophages, and lymphocytes with some necrosis. Inflammation scores were evaluated as described in MATERIALS AND METHODS. N = 6 mice per group; data reported as mean ± SE; * p < 0.05, ** p < 0.01, ***p < 0.001

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