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Table 3 Observed pattern of cells in BAL samples during acute lung AR

From: Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology

Cell

BAL

Reference

Sensitivity

Specificity

Cut-off

Basophils

↑

[37, 38]

   

↑ (rare)

[25]

   

Eosinophils

↑

[59] (experimental)

   

↑

[27, 37, 38, 41, 43]

   

↑ (rare)

[25]

   

0

[32, 70]

   

*

[42]

   

Neutrophils

↑

[32, 37–40]

74 %

82 %

≥12 %

0

[42, 43]

   

Lymphocytes

↑

[47–49] (experimental)

   

↑

[14, 25, 27, 32, 37, 38, 42, 50, 51]

64 %

65 %

40 %

77 %

92.5 %

96 %

≥15 %

>20 %

≥20 %

↑0

[40]

   

NK cells

↓

[25, 85]

   

B cells

↑ (rare)

[25]

   

↑0

[85]

   

Monocytes

↓

[25]

   

Macrophages

↑

[47] (experimental)

   

↓

[27, 32, 40–42, 50]

   
  1. 0, No correlation
  2. ↑, Increased
  3. ↑0, Increased, but statistically not relevant
  4. ↓, Decreased
  5. *, Not detected
  6. (rare), Rarely detected