Table 2 Baseline exercise parameters (full analysis set)
Study 1222.37 | Study 1222.38 | |
|---|---|---|
(n = 147) | (n = 154) | |
Geometric mean (SE) endurance time, s | 414.2 (18.5) | 373.9 (13.5) |
Arithmetic mean (SE) endurance time, s | 478.2 (21.9) | 415.5 (17.4) |
Mean (SE) IC, L | ||
Pre-exercise Isotime End-exercise | 2.29 (0.06) 2.04 (0.07) 2.00 (0.06) | 2.37 (0.06) 2.14 (0.06) 2.13 (0.06) |
Mean (SE) breathing discomfort, Borg units | ||
Pre-exercise Isotime End-exercise | 0.32 (0.05) 5.27 (0.21) 7.20 (0.20) | 0.31 (0.05) 5.53 (0.19) 7.51 (0.18) |
Mean (SE) leg discomfort, Borg units | ||
Pre-exercise Isotime End-exercise | 0.26 (0.07) 5.27 (0.22) 7.05 (0.23) | 0.18 (0.04) 4.42 (0.22) 6.01 (0.24) |
Locus of symptom limitation, n (%) | ||
Breathing discomfort Leg discomfort Breathing and leg discomfort None | 52 (35.4) 40 (27.2) 52 (35.4) 3 (2.0) | 81 (52.6) 26 (16.9) 42 (27.3) 5 (3.2) |