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Fig. 5 | Respiratory Research

Fig. 5

From: Effects of tiotropium + olodaterol versus tiotropium or placebo by COPD disease severity and previous treatment history in the OTEMTO® studies

Fig. 5

(a) FEV1 AUC0–3 and trough FEV1 responses, (b) SGRQ total score and (c) TDI focal score, all at 12 weeks: treatment comparisons for T + O 5/5 μg versus T 5 μg and versus placebo in patients with GOLD A–D disease. FEV1: forced expiratory volume in 1 s; AUC0–3: area under the curve from 0–3 h; SGRQ: St George’s Respiratory Questionnaire; TDI: Transition Dyspnoea Index; T: tiotropium; O: olodaterol; GOLD: Global initiative for chronic Obstructive Lung Disease; CI: confidence interval

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