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Fig. 5 | Respiratory Research

Fig. 5

From: Role of the ion channel, transient receptor potential cation channel subfamily V member 1 (TRPV1), in allergic asthma

Fig. 5

Role of TRPV1 in the rat model. Effect of vehicle (0.5 % MC + 0.2 % tween 80 in saline, 10 ml/kg, i.p., 2 sites; n = 8) or TRPV1 blocker (XEN-D0501, 10 mg/kg) 1 h before and 30 min after challenge in the rat allergic asthma model. The late asthmatic response (LAR) was monitored from 1 h after the end of challenge for 6 h. Panel (a) shows the raw LAR data and panel (b) depicts the mean Area Under the Curve. Data (n = 8) expressed as mean +/− s.e.m. * = p < 0.05 using students T-test (Mann-Whitney)

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