Skip to main content
Fig. 4 | Respiratory Research

Fig. 4

From: Role of the ion channel, transient receptor potential cation channel subfamily V member 1 (TRPV1), in allergic asthma

Fig. 4

Role of TRPV1 in the rat model. Effect of vehicle (0.5 % MC + 0.2 % tween 80 in saline, 10 ml/kg, i.p., 2 sites; n = 8) or TRPV1 blocker (XEN-D0501, 10 mg/kg) 1 h before and 30 min after challenge in the rat allergic asthma model. The following day plasma and BAL fluid was collected. OVA specific IgE levels were measured in the plasma as measured by ELISA (a). Total number of white blood cells (b), eosinophils (c), neutrophils (d) and lymphocytes (e) in the BAL were determined using microscopy using standard morphological criteria. The percentages of the total white cells for each treatment group are: 2, 10 & 9; 22, 68 & 65; 5, 3 & 4, respectively, for eosinophils, neutrophils and lymphocytes. Data expressed as mean +/− s.e.m. * = p < 0.05 using students T-test (Mann-Whitney)

Back to article page