The role of tissue factor and autophagy in pulmonary vascular remodeling in a rat model for chronic thromboembolic pulmonary hypertension

Table 2 TF antigen expression and activity in rat plasma from different groups \( \left(x\pm \mathrm{S}\mathrm{D}\right) \)

Parameters	Subgroup (each n = 15)	Sham	Experimental group
TF antigen
(pg/ml)	1-week	83.24 ± 21.90	170.98 ± 43.06^a
	2-week	82.45 ± 22.76	205.50 ± 45.71^ac
	4-week	83.92 ± 24.11	218.97 ± 35.68^ab
TF activity
(pM/ml)	1-week	62.62 ± 16.06	103.39 ± 22.05^a
	2-week	60.15 ± 17.23	119.54 ± 26.70^ac
	4-week	61.87 ± 16.69	117.12 ± 19.14^ab

TF tissue factor
^aindicated that TF antigen and activity in the experimental group compared to sham operation group (P < 0.05, respectively) in the 1-, 2-, and 4-week subgroups
^bindicated that TF antigen and activity in the 4-week subgroup compared to 1-week subgroup (P >0.05, respectively) and compared to 2-week subgroup (P >0.05, respectively) in the experimental group
^cindicated that TF antigen and activity in the 2-week subgroup compared to 1-week subgroup (P >0.05, respectively) in the experimental group

ISSN: 1465-993X