Parameters | Subgroup (each n = 15) | Sham | Experimental group |
---|
mPAP (mmHg) |
| 1-week | 14.4 ± 2.66 | 18.97 ± 3.87a
|
| 2-week | 13.9 ± 2.82 | 21.89 ± 4.22ad
|
| 4-week | 14.1 ± 3.12 | 25.17 ± 4.74ab
|
WA/TA ratio |
| 1-week | 31.2 ± 6.25 | 46.67 ± 8.50a
|
| 2-week | 30.1 ± 6.01 | 49.06 ± 8.82ad
|
| 4-week | 32.8 ± 6.83 | 54.03 ± 10.26ac
|
-
mPAP mean pulmonary arterial pressure, WA/TA Vessel wall area/total area
-
aindicated that mPAP and WA/TA in the experimental group compared to sham operation group (P < 0.05, respectively) in the 1-, 2-, and 4-week subgroups.
-
bindicated that the mPAP in the 4-week subgroup compared to 1-week subgroup (P <0.05) and 2-week subgroup (P >0.05) in the experimental group.
-
cindicated that the WA/TA in the 4-week subgroup compared to 1-week subgroup (P >0.05) and 2-week subgroup (P >0.05) in the experimental group.
-
dindicated that the mPAP and WA/TA in the 2-week subgroup compared to 1-week subgroup (P >0.05, respectively) in the experimental group