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Fig. 4 | Respiratory Research

Fig. 4

From: The role of tissue factor and autophagy in pulmonary vascular remodeling in a rat model for chronic thromboembolic pulmonary hypertension

Fig. 4

Immunohistochemical analysis of TF, Beclin-1 and LC3B antigen expression in the pulmonary artery. Note: TF antigen was expressed in the pulmonary artery intima of rats in both the sham operation and experimental group. TF antigen expression was low in the pulmonary arterial intima of the sham operation group (a). However, TF antigen expression was increased in the experimental group in 1-, 2-, and 4-week subgroups (b, c, d, respectively). Beclin-1 and LC3B antigen were expressed in the pulmonary artery of rats in both the sham operation and experimental groups. The expression of Beclin-1 (f, g, h) and LC3B (j, k, l) antigen in the experimental groups was lower than in the sham operation group (e, i), especially in the pulmonary arterial intima

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