| |
No-response group
|
Response group
|
P-value
|
|---|
|
BOS diagnosis
|
|
FVC (% predicted)
|
72.27 ± 15.42
|
73.19 ± 12.87
|
.838
|
|
FEV1 (% predicted)
|
56.46 ± 16.05
|
56.73 ± 15.52
|
.959
|
|
FEV1/FVC (%)
|
63.64 ± 10.54
|
63.83 ± 16.29
|
.970
|
|
RV (% predicted)
|
103.50 ± 39.10
|
116.68 ± 35.88
|
.307
|
|
TLC (% predicted)
|
82.30 ± 11.58
|
90.57 ± 12.07
|
.054
|
|
RV/TLC (%)
|
37.80 ± 10.76
|
40.93 ± 9.59
|
.366
|
|
DLCO (% predicted)
|
58.40 ± 21.81
|
63.30 ± 16.49
|
.429
|
|
Pre-HSCT – BOS diagnosisa
|
|
Δ FVC (% predicted)
|
12.45 ± 13.28
|
23.59 ± 15.88
|
.036
|
|
Δ FEV1 (% predicted)
|
30.81 ± 18.16
|
40.61 ± 18.89
|
.126
|
|
Δ FEV1/FVC (%)
|
18.18 ± 12.78
|
14.46 ± 15.63
|
.467
|
|
Δ RV (% predicted)
|
−20.20 ± 32.45
|
−36.63 ± 35.90
|
.194
|
|
Δ TLC (% predicted)
|
3.90 ± 13.85
|
3.63 ± 11.25
|
.948
|
|
Δ RV/TLC (%)
|
−9.90 ± 7.69
|
−14.08 ± 10.17
|
.232
|
|
Δ DLCO (% predicted)
|
−1.00 ± 20.75
|
−0.51 ± 16.73
|
.937
|
-
aFour missing values in Pre-HSCT (N = 57). Data represent the mean ± SD. P-values shown in bold are significant at the 0.05 level. HSCT hematopoietic stem cell transplantation, BOS bronchiolitis obliterans syndrome, FVC forced vital capacity, FEV1 forced expiratory volume in 1s, RV residual volume, TLC total lung capacity, DLCO carbon monoxide diffusion in the lung
