Fig. 1

Lung inflammatory reaction after instillation of whole gastric fluid. Light microscopy (hematoxylin-eosin) of rat lung at 4, 12, and 24 h and, at days 4 and 7 after gastric fluid instillation. Intra-alveolar inflammatory and red blood cells along with proteinaceous material are seen at 4 h, with a peribronchiolar distribution. At 12 and 24 h, the inflammatory infiltrate is more intense with coalescence of affected areas and patchy consolidation. At days 4 and 7, intra-alveolar buds of granulation tissue (arrows) along with foreign-body giant cells, either isolated or forming granulomas are seen. Original magnification: 100×. C: control; d: days; h: hours