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Fig. 8 | Respiratory Research

Fig. 8

From: Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways

Fig. 8

Semiquantitative measurement of anti-IAV activities of SLIGRL-amide in human isolated bronchiolar segments by immunohistochemical staining of IAV nucleoprotein. a Immunohistochemical staining of IAV in sections of human isolated bronchiolar segments exposed to IAV in the absence (upper image) or presence of SLIGRL-amide (lower image), for 15 min. After 48 h of perfusion with media, segments were fixed, paraffin-embedded, sectioned and immunohistochemically stained for IAV. Bar = 50 μm. b Levels of staining for immunoreactive IAV nucleoprotein in the bronchiolar epithelium of perfused human airways exposed to saline or SLIGRL-amide. Shown are representative images from at least 4–9 experiments using airways from different donors. *, indicates P <0.05, compared to IAV + saline control (one-way ANOVA)

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