Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study

Table 4 Reasons for poor asthma control, according to patients’ and doctors’ perspective

Reasons for poor control^a: n = 4585	Patients’ perspective n (%)	Doctors’ perspective n (%)	Kappa coefficient^b
Seasonal worsening Continued exposure to allergens/irritants/triggers Comorbidities Poor adherence to therapy Inadequate therapy Poor efficacy of therapy Active smoking Depression Passive smoking Inadequate inhalation technique Poor patient-physician communication Poor tolerability of therapy Co-administration of drugs Incorrect diagnosis	1848 (40.3) 1148 (25.0) 769 (16.8) 507 (11.1) 571 (12.5) 675 (14.7) 339 (7.4) 388 (8.5) 421 (9.2) 104 (2.3) 78 (1.7) 97 (2.1) 70 (1.5) 57 (1.2)	1756 (38.3) 1270 (27.7) 1028 (22.4) 965 (21.0) 868 (18.9) 622 (13.6) 462 (10.1) 453 (9.9) 319 (7.0) 195 (4.3) 197 (4.3) 100 (2.2) 68 (1.5) 40 (0.9)	0.72 0.73 0.68 0.47 0.56 0.53 0.81 0.67 0.64 0.39 0.27 0.44 0.55 0.30

N number of patients
^aMore than one reason could be indicated
^bKappa agreement interpretation: <0: poor, 0.01–0.20: slight, 0.21–0.40: fair, 0.41–0.60: moderate, 0.61–0.80: good, 0.81–1.00; very good

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