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Table 1 Demographic and clinical characteristics of participants

From: Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study

 

Controlled

n = 3526 (43.5)

Partly controlled

n = 1462 (18.0)

Uncontrolled

n = 3123 (38.5)

Overall p-value*

Overall population

n = 8111 (100.0)

Age [years], mean (SD)

49 (16)

49 (16)

52 (15)

<.001

50 (16)

Age categories (years), n (%)

   

<.001

 

  ≤ 39

991 (30.1)

407 (30.0)

572 (21.9)

 

1970 (27.1)

 40–64

1612 (49.0)

694 (51.1)

1519 (58.2)

 

3825 (52.7)

  ≥ 65

688 (20.9)

257 (18.9)

518 (19.9)

 

1463 (20.2)

Gender, n (%)

     

 Female

2207 (62.8)

996 (68.3)

2184 (70.1)

<.001

5387 (66.6)

Body mass index categories, n (%)

   

<.001

 

 Normal weight (≥18.5 and <25 kg/m2)

1469 (41.7)

545 (37.3)

1044 (33.4)

 

3058 (37.7)

 Obese (≥30 kg/m2)

763 (21.7)

384 (26.3)

968 (31.0)

 

2115 (26.1)

 Overweight (≥25 and <30 kg/m2)

1238 (35.1)

505 (34.5)

1069 (34.2)

 

2812 (34.7)

 Underweight (<18.5 kg/m2)

53 (1.5)

28 (1.9)

42 (1.3)

 

123 (1.5)

Living environment, n (%)

   

0.038

 

 Rural

871 (26.8)

412 (30.0)

792 (27.1)

 

2075 (27.5)

 Urban

2374 (73.2)

960 (70.0)

2131 (72.9)

 

5465 (72.5)

Education, n (%)

   

<.001

 

 None

54 (1.8)

13 (1.0)

52 (1.9)

 

119 (1.7)

 Primary/middle school

1122 (36.9)

528 (39.9)

1235 (45.7)

 

2885 (40.8)

 High school

1179 (38.8)

461 (34.8)

890 (32.9)

 

2530 (35.8)

 Graduate/Post Graduate

685 (22.5)

321 (24.3)

528 (19.5)

 

1534 (21.7)

Employment status, n (%)

   

<.001

 

 Employed

1811 (56.8)

734 (54.0)

1310 (45.1)

 

3855 (51.8)

 Unemployed/housewife/student

602 (18.9)

263 (19.3)

553 (19.1)

 

1418 (19.0)

 Retired/Unable to work

773 (24.3)

363 (26.7)

1039 (35.8)

 

2175 (29.2)

Occupational exposure to allergens/irritants among employed, n (%)

581 (32.1)

294 (40.1)

542 (41.4)

0.008

1417 (36.8)

Smoking habits, n (%)

   

<.001

 

 Never-smoker

2312 (66.6)

913 (63.8)

1966 (63.8)

 

5191 (65.0)

 Current Smoker

314 (9.0)

182 (12.7)

425 (13.8)

 

921 (11.5)

 Ex-Smokera

846 (24.4)

337 (23.5)

691 (22.4)

 

1874 (23.5)

Smoking history pack yearsb, mean (SD)

14 (14)

15 (14)

16 (16)

<.001

15 (15)

Pack years ≥10, n (%)

588 (51.9)

280 (55.9)

641 (58.5)

0.007

1509 (55.3)

Allergies, n (%)

   

0.059

 

 Yes

2327 (68.6)

953 (67.3)

1992 (65.8)

 

5272 (67.3)

 No

1065 (31.4)

463 (32.7)

1035 (34.2)

 

2563 (32.7)

Frequent allergiesc

     

 Inhalants, n (%)

2148 (92.3)

861 (90.3)

1783 (89.5)

0.005

4792 (90.9)

 Drugs, n (%)

247 (10.6)

115 (12.1)

312 (15.7)

<.001

674 (12.8)

 Foods, n (%)

219 (9.4)

98 (10.3)

207 (10.4)

0.520

524 (9.9)

Comorbidities relevant to respiratory tractd, n (%)

 Allergic rhinitis

976 (55.8)

452 (57.6)

860 (50.3)

<.001

2288 (53.9)

 Hypertension

508 (29.0)

247 (31.5)

629 (36.8)

<.001

1384 (32.6)

 Gastro − esophageal reflux

351 (20.1)

181 (23.1)

500 (29.2)

<.001

1032 (24.3)

 Chronic rhinosinusitis

259 (14.8)

96 (12.2)

276 (16.1)

0.040

631 (14.9)

 Psychological disturbances

145 (8.3)

95 (12.1)

333 (19.5)

<.001

573 (13.5)

 Respiratory infections

105 (6.0)

81 (10.3)

288 (16.8)

<.001

474 (11.2)

 Nasal polyposis

165 (9.4)

54 (6.9)

150 (8.8)

0.107

369 (8.7)

 Obstruction Sleep Apnea Syndrome

74 (4.2)

33 (4.2)

92 (5.4)

0.216

199 (4.7)

 Congestive heart failure

27 (1.5)

27 (3.4)

113 (6.6)

<.001

167 (3.9)

Outpatients visitse

 Mean (SD)

5.3 (5.6)

6.9 (6.5)

8.3 (7.7)

<001

6.7 (6.8)

 Patients with at least one visit, n (%)

3353 (95.1)

1399 (95.7)

2996 (95.9)

0.241

7748 (95.5)

  1. The percentages have been calculated based on the number of available data for each variable
  2. n number of patients, SD standard deviation
  3. *p-value based on Chi-square for categorical variables and Kruskal-Wallis test for quantitative variables
  4. aPatients who stopped smoking at least one year prior to study start
  5. bRefers to current smokers and ex-smokers
  6. cThe percentages are calculated based on the number of patients with allergies
  7. dPatients could have more than one comorbidity
  8. eIncluding visits to respiratory physician, allergologist, other specialist and general practitioner in the last 12 months