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Fig. 2 | Respiratory Research

Fig. 2

From: The effect of aclidinium bromide on daily respiratory symptoms of COPD, measured using the Evaluating Respiratory Symptoms in COPD (E-RS: COPD) diary: pooled analysis of two 6-month Phase III studies

Fig. 2

Change from baseline in E-RS scores and proportion of E-RS responders at Week 24, overall and by GOLD group a and b RS-Total score; c and d RS-Breathlessness domain; e and f RS-Cough & Sputum domain; g and h RS-Chest Symptoms domain. *p < 0.05, **p < 0.01, ***p < 0.001 vs placebo. Change from baseline data are LS means (SE). Responder data are OR (95 % CI). aplacebo n = 578; aclidinium n = 583; bplacebo n = 72; aclidinium n = 64; cplacebo n = 506; aclidinium n = 519. BID, twice daily; CI, confidence interval; E-RS, Evaluating Respiratory Symptoms; GOLD, Global initiative for chronic Obstructive Lung Disease; LS, least squares; OR, odds ratio; SE, standard error

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Respiratory Research

ISSN: 1465-993X

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