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Table 3 Intraclass correlation coefficients for clinical characteristics over all study visits

From: Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

ICC (95 % CI) [number of visits]

Mild (n = 52)

Moderate (n = 55)

Severe (n = 51)

All asthma (n = 158)

FEF2575, pre-BD

0.80 (0.73–0.87) [4.5]

0.76 (0.68–0.84) [4.6]

0.67 (0.56–0.77) [4.7]

0.82 (0.78–0.86) [4.6]

FEV1/FVC, pre-BD

0.86 (0.80–0.91) [4.5]

0.79 (0.71–0.86) [4.6]

0.84 (0.77–0.89) [4.7]

0.88 (0.85–0.90) [4.6]

FEV1 % predicted, pre-BD

0.72 (0.62–0.81) [4.5]

0.60 (0.48–0.71) [4.6]

0.64 (0.52–0.75) [4.7]

0.81 (0.77–0.85) [4.6]

FVC % predicted, pre-BD

0.79 (0.71–0.86) [4.5]

0.62 (0.51–0.73) [4.5]

0.75 (0.66–0.83) [4.7]

0.79 (0.74–0.83) [4.6]

PEFR, pre-BD

0.83 (0.76–0.89) [4.5]

0.81 (0.73–0.87) [4.6]

0.86 (0.80–0.91) [4.7]

0.86 (0.83–0.89) [4.6]

FEV1 change post-BD (% predicted)

0.45 (0.32–0.59) [4.5]

0.39 (0.26–0.53) [4.5]

0.39 (0.26–0.54) [4.6]

0.42 (0.35–0.50) [4.5]

FEV1 change post-BD (L)

0.45 (0.32–0.59) [4.5]

0.53 (0.41–0.66) [4.5]

0.47 (0.34–0.61) [4.6]

0.48 (0.41–0.56) [4.5]

FENO, ppb (log)

0.64 (0.51–0.75) [3.6]

0.78 (0.69–0.86) [3.6]

0.75 (0.65–0.84) [3.6]

0.73 (0.67–0.78) [3.6]

ACQ-7

0.61 (0.48–0.73) [3.6]

0.57 (0.43–0.69) [3.6]

0.55 (0.41–0.69) [3.7]

0.65 (0.58–0.71) [3.6]

AQLQ

0.74 (0.63–0.82) [3.6]

0.82 (0.74–0.88) [3.6]

0.78 (0.68–0.85) [3.7]

0.79 (0.74–0.83) [3.6]