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Fig. 2 | Respiratory Research

Fig. 2

From: CD4+ and CD8+ T cells play a central role in a HDM driven model of allergic asthma

Fig. 2

Selection of optimum sensitising route and dose. Male C57bl/6 mice were sensitised with vehicle or HDM (0.005–500 μg/kg HDM) either i.n. or i.p. (with or without Alum). Levels of total IgE in plasma were measured by ELISA. The dose and route selected for further model investigation is indicated by the black arrow. Data (n = 6–12) expressed as mean total IgE levels (ng/ml) ± S.E.M. *p < 0.05 vs. respective saline challenged controls, Kruskal-Wallis one-way ANOVA followed by Dunn’s Multiple Comparison post-test

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